The committee is not thinking this when determining the national seeds. This step in the process is solely based on their assessment of merit (even if you do not agree with their definition of merit).
I agree re:Missouri. It is unfortunate that LSU is not required to face someone like Ole Miss ... or even South Carolina in the opener.
That said, if the Cajuns get South Alabama/Texas State/Texas State ... and go undefeated ... the Cajuns could catch LSU in the RPI.
Brian