I would prefer what is best for the program (not the city & fans), and that is going to WCWS. Yes, we eventually would have to play the best (Oklahoma), but I'd rather play them in the WCWS championship than in a Super Regional.
Just getting to OKC helps the program recruit better, schedule better opponents, sell more tickets, grow the fan base, expand our brand, etc. All of those things lead to a nationally respected elite softball team, which is better (long-term) for the city and the fans.
The above statement is my personal opinion. I understand that some people feel it is always best to host (even if you are the 16th seed).