So the 49ers have the best defense in the league? Interesting, so what happens when the Eagles beat the brakes off the 49ers this weekend? I hate to break it to you man genius. But you're really out of your league now. The Eagles are going to win this game by at least two scores. I won't bother your superior intelligence by boring you with the reasons why. I'm just stating for the record that all the San Fran love ends tragically this weekend.