HIV vaccines should avoid viral target cells, primate model study suggests
Vaccines designed to protect against HIV have backfired in clinical trials. Non-human primate model studies suggest an explanation: vaccination may increase the number of immune cells that serve as viral targets. In a nonhuman primate model of HIV transmission, higher levels of viral target cells in gateway mucosal tissues were associated with an increased risk of infection.<img src="//feeds.feedburner.com/~r/sciencedaily/~4/thrB7jrmifU" height="1" width="1" alt=""/>